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Isotretinoin

Isotretinoin 20mg · Multiple manufacturers · Schedule H

The nuclear option for acne. Retinoid that fundamentally changes sebaceous gland function. Dermatologist-supervised 6-month protocol with required blood monitoring. Not first-line, but when nothing else works.

₹1,499
/month
Includes: Doctor consultation · Prescription · Medication · Delivery
Have questions? Chat with us on WhatsApp
How your protocol works
1
Purchase
Secure checkout via Razorpay
2
Doctor calls
Licensed physician within 2hrs
3
Rx issued
Prescription after evaluation
4
Ships
Delivered within 48hrs
Duration
6 months
Monitoring
Monthly bloodwork
Clearance
85%+ after course
Dose
20mg/day
Pharmacology

How isotretinoin works

Isotretinoin is the most powerful anti-acne medication available, working through multiple mechanisms to permanently reduce sebum production and prevent bacterial colonization. This is not a symptomatic treatment—it addresses the root cause.

Sebaceous Gland Atrophy
Dramatically reduces sebum production by causing permanent shrinkage of oil glands. The most significant mechanism—rarely achieved by other treatments.
Comedolysis
Normalizes follicular keratinization, preventing the pore blockage that initiates acne formation. Restores normal skin turnover.
Anti-inflammatory & Antibacterial
Reduces Propionibacterium acnes colonization and dampens inflammatory mediators. Suppresses the inflammatory cascade underlying acne.
Evidence

Clinical data

Isotretinoin has the strongest evidence for acne resolution of any medication. The data is consistent: most patients achieve near-complete clearance and maintain it long-term.

85%+
Clearance after full course
Multiple RCTs and clinical practice
6 months
Standard treatment duration
FDA-approved protocol
Monthly
Liver function monitoring
Mandatory safety requirement
Protocol

How to get started

01
Initial Bloodwork
Baseline liver function & lipid panel
02
Dermatology Evaluation
Doctor assesses candidacy & explains risks
03
Monthly Monitoring
Blood tests & clinical review each month
04
6-Month Course
Complete protocol with dosing adjustment
FAQ

Common questions

How does isotretinoin work?
Isotretinoin acts through three primary mechanisms: it causes sebaceous gland shrinkage (permanently reducing sebum), normalizes skin cell turnover to prevent pore clogging, and reduces bacterial colonization. Together, these address acne at its root—not just symptoms.
What are the side effects and risks?
Common side effects include dry skin, dry lips, dry eyes, and photosensitivity. Serious but rare: teratogenicity (severe birth defects if pregnant), liver inflammation, lipid elevation. Monthly bloodwork catches complications early. Your dermatologist will discuss all risks before starting.
Why is bloodwork required?
Isotretinoin can affect liver enzymes and lipid levels. Monthly monitoring ensures your liver and lipid profiles remain healthy throughout treatment. This is a safety requirement, not optional.
Can I drink alcohol?
Alcohol should be minimized or avoided entirely. Isotretinoin can affect liver function, and alcohol adds additional liver stress. Discuss with your dermatologist for personalized guidance.
How long until I see clear skin?
Initial improvement appears within 2-3 months. Significant clearance usually occurs by 4-5 months. The majority of patients achieve near-complete clearance by the end of the 6-month course. Results persist long-term in 80-90% of patients.
Get Started

Ready to clear?

Book a consultation with a dermatologist to determine if isotretinoin is appropriate for your acne severity.

Have questions? Chat with us on WhatsApp