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Melatonin 5mg

Melatonin 5mg · Multiple manufacturers · Schedule H (high-dose)

High-dose prescription melatonin. Not the 0.5mg supplement—the clinical-grade circadian rhythm reset. For jet lag, shift work, delayed sleep phase syndrome, and anyone whose sleep architecture needs a rebuild.

₹499
/month
Includes: Doctor consultation · Prescription · Medication · Delivery
Have questions? Chat with us on WhatsApp
How your protocol works
1
Purchase
Secure checkout via Razorpay
2
Doctor calls
Licensed physician within 2hrs
3
Rx issued
Prescription after evaluation
4
Ships
Delivered within 48hrs
Dose
5mg clinical
Timing
30 min before bed
Duration
4–8 week protocol
Schedule
Schedule H (high)
Pharmacology

How melatonin works

Melatonin is your body's master circadian regulator. Clinical-grade 5mg doses directly reset the suprachiasmatic nucleus (SCN), your brain's 24-hour clock, and trigger the thermoregulatory cascade that initiates sleep.

MT1/MT2 Receptor Agonism
Activates melatonin receptors in the suprachiasmatic nucleus (SCN), directly resetting your circadian clock. Shifts sleep phase within 3-7 days.
Core Body Temperature Regulation
Initiates the thermoregulatory cascade that lowers core body temperature, the primary physiological trigger for sleep onset.
Antioxidant & Neuroprotection
Potent free radical scavenger. At clinical doses (5mg), melatonin provides neuroprotective benefits beyond simple sleep induction.
Evidence

Clinical data

Prescription melatonin has extensive evidence for circadian rhythm disorders. 5mg is the validated optimal dose for phase-shifting, with onset of effect in 3-7 days.

3–7
Days to circadian reset
Clinical trial data
5mg
Optimal phase-shift dose
Consensus from sleep medicine
Neuroprotective
At clinical doses
Antioxidant and protective effects
Protocol

How to get started

01
Sleep Consultation
Discuss sleep issues and circadian needs
02
Sleep Assessment
Doctor evaluates sleep phase and timing needs
03
Prescription
5mg melatonin with timing instructions
04
Tracking & Adjustment
Monitor sleep improvement, adjust timing as needed
FAQ

Common questions

Why prescription melatonin vs supplement?
Supplements (0.5mg) are sub-therapeutic. Prescription 5mg provides clinical-grade circadian resetting power. Higher dose ensures adequate SCN receptor saturation and reliable phase-shifting within days.
Is 5mg too much?
No. 5mg is the validated optimal dose for circadian rhythm disorders. Melatonin has an excellent safety profile even at higher doses. You cannot "overdose" on melatonin—excess is simply excreted.
Can I take it long-term?
Yes, melatonin is safe for long-term use. Many people use it indefinitely. Standard protocols are 4-8 weeks to reset circadian rhythm, then assess if needed long-term. Your doctor will guide duration.
Interaction with other sleep aids?
Melatonin is generally safe to combine with other treatments, but discuss with your doctor. Combining with benzodiazepines increases drowsiness. Your physician will personalize based on your specific situation.
When exactly should I take it?
Take 30 minutes before your desired bedtime. For jet lag: take 30 min before bedtime in your destination timezone. For shift work: take 30 min before your desired sleep time. Timing is critical for phase-shifting effect.
Get Started

Ready to reset?

Consult a sleep specialist about clinical-grade melatonin therapy.

Have questions? Chat with us on WhatsApp