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Longevity

Rapamycin 1mg

Sirolimus 1mg · Multiple manufacturers · Schedule H

The mTOR inhibitor that has anti-aging researchers paying very close attention. Originally an immunosuppressant, now studied for its remarkable effects on lifespan extension across every organism tested. The most promising longevity drug in clinical research.

₹4,999
/month
Includes doctor consultation, prescription, medication & delivery
Have questions? Chat with us on WhatsApp
How your protocol works
1
Purchase
Secure checkout via Razorpay
2
Doctor calls
Licensed physician within 2hrs
3
Rx issued
Prescription after evaluation
4
Ships
Delivered within 48hrs
Half-life
62 hours
Dosing Protocol
Weekly (low-dose)
Origin
Easter Island soil
Schedule
H (Rx)
Pharmacology

How rapamycin works

Rapamycin inhibits mTOR (mechanistic target of rapamycin), the master regulator of cellular growth. By suppressing mTORC1, rapamycin shifts cells from anabolic growth mode into catabolic maintenance and repair—the cellular state associated with longevity across species.

mTORC1 Inhibition
Selectively inhibits mTOR complex 1, the master growth regulator. Shifts cells from growth to maintenance/repair—the state associated with extended lifespan in model organisms.
Autophagy Induction
Upregulates cellular autophagy—the cleanup of damaged proteins and organelles. Enhanced autophagy removes senescent components and improves mitochondrial quality.
Senescent Cell Clearance
Emerging evidence suggests rapamycin reduces senescent cell burden—aged, dysfunctional cells that drive inflammation and age-related disease.
Evidence

Clinical data

Rapamycin is the most studied longevity drug across model organisms. From yeast to mice to primates, consistent lifespan extension has been documented. In mice, the NIA Intervention Testing Program showed 9–14% lifespan extension—one of the largest effects of any single intervention.

9–14%
Lifespan extension in mice
NIA ITP (National Institute on Aging)
Improved
Immune function in elderly
2014 Novartis clinical trial
Consistent
Results across species
Yeast, worms, flies, mice, primates
Protocol

How to get started

01
Book Consultation
Connect with a licensed physician via WhatsApp
02
Medical Evaluation
Doctor reviews your health status and baseline labs
03
Prescription
If appropriate, prescription issued with monitoring plan
04
Delivered
Ships from licensed pharmacy within 24 hours
FAQ

Common questions

Is rapamycin safe for longevity use?
Rapamycin has decades of safety data from organ transplant patients taking much higher doses. For longevity use, dosing is dramatically lower (1mg weekly vs. 5+ mg daily). Side effects at low dose are minimal. Physician oversight and baseline labs are essential.
What is mTOR?
mTOR (mechanistic target of rapamycin) is a master cellular regulator that controls growth, protein synthesis, and metabolic rate. It's central to aging: constantly active mTOR drives growth at the expense of maintenance. Inhibiting mTOR shifts the cell-survival calculus toward longevity.
What dosing protocol is recommended?
Most longevity researchers use 1mg once per week. Some use 5mg weekly. Dosing varies by individual. Your physician will determine the optimal dose based on your baseline, goals, and tolerance. Labs (lipid panel, glucose, renal function) should be monitored.
Side effects at low dose?
At longevity doses (1mg/week), rapamycin is well-tolerated. Minor effects include mouth sores, elevated cholesterol, and glucose changes—mostly reversible. Immunosuppression is dose-dependent; at low dose, immune function may actually improve. Regular monitoring essential.
Is it available in India?
Yes. Rapamycin (Sirolimus) is a Schedule H drug in India, available under brand names like Rapamune and generics. It's manufactured domestically at a fraction of US costs. Available via arq with physician consultation and valid prescription.
What's included in the ₹4,999/month protocol price?
The monthly protocol price includes the doctor consultation with baseline health and lab review, prescription issuance after medical evaluation, rapamycin medication (typically 1-5mg weekly based on your protocol), and delivery to your door within 48 hours. No hidden fees—what you see is what you pay. Regular monitoring labs are coordinated separately.
Get Started

Ready to extend lifespan?

Book a consultation with a licensed physician to discuss whether rapamycin is appropriate for your longevity protocol.

Have questions? Chat with us on WhatsApp