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Tretinoin

Tretinoin 0.05% cream 30g · Multiple manufacturers · Schedule H

The gold standard retinoid. 50+ years of evidence for anti-aging, acne, hyperpigmentation, and skin texture. The one product dermatologists actually use themselves.

₹899
/month
Includes: Doctor consultation · Prescription · Medication · Delivery
Have questions? Chat with us on WhatsApp
How your protocol works
1
Purchase
Secure checkout via Razorpay
2
Doctor calls
Licensed physician within 2hrs
3
Rx issued
Prescription after evaluation
4
Ships
Delivered within 48hrs
Application
Nightly topical
Onset
6–12 weeks
Concentration
0.025–0.1%
Tube
30g/month
Pharmacology

How tretinoin works

Tretinoin (all-trans retinoic acid) binds to retinoid receptors in the nucleus, directly modifying gene expression to accelerate cell turnover and stimulate collagen synthesis. It's not a symptom mask—it literally rebuilds skin at the cellular level.

Retinoid Receptor Activation
Binds RAR (retinoic acid receptors), increasing cell turnover 2-3x and accelerating the replacement of photodamaged skin with fresh, healthy cells.
Collagen & Elastin Synthesis
Stimulates production of collagen I and III, and increases elastin. Studies show 80% increase in collagen after 12 weeks of use.
Melanin Regulation
Inhibits tyrosinase activity and increases melanin clearance, fading hyperpigmentation and melasma over time.
Evidence

Clinical data

Tretinoin has the most robust evidence base of any topical anti-aging ingredient. Five decades of clinical research consistently demonstrate efficacy across photoaging, acne, and pigmentation.

50+
Years of clinical evidence
FDA-approved since 1971
80%
Collagen increase (12 wks)
Peer-reviewed dermatology studies
6–12
Weeks to visible results
Standard clinical timeline
Protocol

How to get started

01
Book Consultation
Connect with a dermatologist via WhatsApp
02
Skin Assessment
Doctor evaluates your skin type and sensitivities
03
Prescription & Guidance
Tretinoin prescribed with detailed usage instructions
04
Monthly Support
Follow-ups to monitor tolerance and adjust strength
FAQ

Common questions

When will I see results?
Initial benefits like improved skin smoothness appear in 4-6 weeks. Fine line reduction and texture improvement visible by 8-12 weeks. Significant collagen-building effects emerge at 3-6 months. Hyperpigmentation fading takes 3-6 months or longer.
What is the purging phase?
Tretinoin increases skin cell turnover, which can temporarily bring deep comedones to the surface as breakouts. This "purging" typically lasts 4-8 weeks and is a sign the retinoid is working. It resolves as your skin adapts.
Can I use it in summer?
Yes, but with strict sun protection. Tretinoin increases photosensitivity, so broad-spectrum SPF 30+ is mandatory daily, even on cloudy days. Many dermatologists recommend starting in winter for easier tolerance.
Is tretinoin safe during pregnancy?
Tretinoin is contraindicated during pregnancy due to teratogenic risk (birth defects). If planning pregnancy or already pregnant, discontinue tretinoin and consult your OB/GYN. Switch to safer alternatives like azelaic acid.
How to layer with other products?
Apply tretinoin to completely dry skin after your cleanser. Wait 10-15 minutes before applying other actives or moisturizer. Avoid combining with vitamin C, AHA/BHA, or benzoyl peroxide initially. Use only gentle, hydrating products alongside tretinoin.
Get Started

Ready to transform?

Consult with a dermatologist to start tretinoin therapy tailored to your skin.

Have questions? Chat with us on WhatsApp